Physiology

Biochemical Pathways in Humans

 Acid-Base

Conforming to a Brønsted–Lowry definition, the Stewart (physical chemistry) approach should be adopted. This is based on charge interactions (redox reactions) in human plasma, which serve as the independent control mechanisms for pH determination. This is an extremely accurate approach, and only has three parameters to consider:

  • pCO2
  • Weak acids (mostly albumin)
  • Strong ion difference (SID)

Cellular Respiration – overview

Acetyl-CoA lies at the crossroads of cellular metabolism

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Glycolysis

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Krebs cycle

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Oxidative Phosphorylation

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Pentose Phosphate Pathway

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Protein Metabolism

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Heme metabolism

Heme-containing proteins

  • Haemoglobin
  • Myoglobin
  • Cytochromes
  • Catalase
  • some peroxidases

Getting the Heme out of your globin

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Nucleosides, Uric Acid and Urea Cycle

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Lipid Metabolism

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